唐艺芝，副研究员，博士生导师

在生物学一级学科招收博士、硕士研究生，招生方向：微生物学、动物医学、生物信息学

Email: tangyizhi23@163.com

电话： 028-85471599

1.学习及工作经历

2005.09 – 2010.06  吉林大学 动物医学 本科

2013.09 – 2013.06  吉林大学 人兽共患病研究所 硕士

2013.09 – 2017.04 Iowa State University 兽医微生物 博士

2017.05 – 2017.09 Iowa State University 博士后

2018.07 – 至今  四川老员工命科学公司 副研究员

2.研究方向

长期从事动物疫病防控，动物源细菌耐药性及致病性方面的研究。兼任四川省特聘专家、畜牧兽医学会禽病学分会副秘书长，四川省高致病性禽流感防控指导专家组成员，四川省畜牧兽医学会理事。讲授全英文《微生物学》、《动物健康与食品安全》。研究成果在Journal of Antimicrobial Chemotherapy, Veterinary Microbiology, Antimicrobial Agents and Chemotherapy等期刊发表。副主编《动物源细菌耐药性》专著1部。

3.在研项目

1) 国家自然科学基金面上项目，32273061，氟苯尼考促进弯曲菌中外膜囊泡介导的耐药基因转移机制研究，2023.01- 2026.12，主持

2) 十四五国家重点研发项目子课题，2022YFC2303904，食源性病原菌交叉耐药基因传播机制及阻断技术，2022.12- 2025.11, 主持

3) 四川省“十四五”川猪重大科技专项课题，2021ZDZX0010，川猪重大疫病防控新技术新产品创制，2021.07- 2026.06，主持

4) 四川省科技厅面上项目，2023NSFSC0174，恩诺沙星促进弯曲菌中外膜囊泡介导的耐药基因转移机制研究，2023. 01- 2024.12，主持

5）四川省重点项目子课题，2020YFN0147-LH，川猪产业链提质增效关键技术研究与集成示范-生猪精准化疫病防控关键技术，2020.01-2023.12，主持

6）2020年入选四川省人才计划。

4.代表性文章

1)Mengyu Zhao^#, Shuang He^#, Renqiao Wen, Chao Li, Xinggui Chen, Xiaolong Lin, Hongning Wang, Yizhi Tang*. Membrane vesicles derived from Enterococcus faecalis promote the cotransfer of important antibiotic resistance genes located on both plasmids and chromosomes. International Journal of Antimicrobial Agents. (In revision)

2) Zihao Song, Yue Yu, Xinpeng Bai, Yiguo Jia, Jiayi Tian, Kui Gu, Mengyu Zhao, Changyu Zhou, Xiangyu Zhang, Hongning Wang, Yizhi Tang*. Pathogen-Specific Bactericidal Method Mediated by Conjugative Delivery of CRISPR-Cas13a Targeting Bacterial Endogenous Transcripts. Microbiol Spectr. 2022 Aug 31;10(4): e0130022.

3) Renqiao Wen, Chao Li, Mengyu Zhao, Hongning Wang, Yizhi Tang*. Withdrawal of antibiotic growth promoters in China and its impact on the foodborne pathogen Campylobacter coli of swine origin. Front Microbiol. 2022 Sep 8;13: 1004725.

4) Yizhi Tang, Yan Lai, Linghan Kong, Xingyuan Wang, Cui Li, Yulong Wang, Changwei Lei, Hongning Wang. Characterization of three porcine Escherichia coli isolates co-harbouring tet(X4) and cfr. Journal of Antimicrobial Chemotherapy. J Antimicrob Chemother. 2021 Jan 1;76(1):263-264.

5) Yizhi Tang, Yan Lai, Xingyuan Wang, Changwei Lei, Chao Li, Linghan Kong, Yulong Wang, Hongning Wang*. Novel insertion sequence ISChh1-like mediating acquisition of optrA gene in foodborne pathogen Campylobacter coli of swine origin. Vet Microbiol. 2020 Nov 25;252:108934.

6) Yizhi Tang, Yan Lai, Xiaotong Yang, Xiaotong Cao, Youwei Hu, Xingyuan Wang, Hongning Wang. Genetic environments and related transposable elements of novel cfr(C) variants in Campylobacter coli isolates of swine origin. Veterinary Microbiology. 2020 Aug; 247:108792.

7) Biao Tang ^#, Yizhi Tang ^#, Ling Zhang, Xiao Liu, Jiang Chang, Xiaodong Xia, Hua Yang, Zhangqi Shen*. Emergence of fexA in Mediating Resistance to Florfenicols in Campylobacter. Antimicrob Agents Chemother. 2020 Jun 23;64(7): e00260-20. (co-first author)

8) Yizhi Tang, Liangxing Fang, Changyun Xu, Qijing Zhang#. Antibiotic resistance trends and mechanisms in the foodborne pathogen, Campylobacter[J]. Anim Health Res Rev, 2017:1-12. 4). Yizhi Tang, Richard J. Meinersmann, Qijing Zhang# et al. Wide but variable distribution of a hypervirulent Campylobacter jejuni clone in beef and dairy cattle in the United States. Applied & Environmental Microbiology, 2017, 83(24): AEM.01425-17.

9) Yizhi Tang, Lei Dai, Orhan Sahin, Zuowei Wu, Mingyuan Liu, Qijing Zhang*. Emergence of a plasmid-borne multidrug resistance gene cfr(C) in foodborne pathogen Campylobacter. Journal of Antimicrobial Chemotherapy, 2017, 72(6).

10) Yizhi Tang, Orhan Sahin, Nada Pavlovic, Jeff LeJeune, James Carlson, Zuowei Wu, Lei Dai, Qijing Zhang*. Rising fluoroquinolone resistance in Campylobacter isolated from feedlot cattle in the United States. Scientific reports, 2017 Mar 29; 7(1):494.