彭锐 副研究员/硕导
联系方式:pengrui@scu.edu.cnpengrui@ymail.com
学习工作经历:
2001.9-2005.6 四川农业大学动物科技公司学士
2005.9-2008.6 四川老员工命科学公司 硕士
2010.2-2012.2 美国匹兹堡大学(University of Pittsburgh)癌症研究中心联培博士生
2008.9-2012.6 四川老员工命科学公司 博士
2012.7-2013.1 中国科公司昆明动物研究所 助理研究员
2013.7-至今 四川老员工命科学公司副研究员
研究方向:
1.结肠癌中Bcl-2蛋白家族在线粒体凋亡途径中的作用和调节机制
2.诱导多功能干细胞(iPSc)技术在濒危动物的繁殖和保护中的应用
在研课题:
1. 国家自然科学青年基金促凋亡蛋白Bax泛素化位点的鉴定及其功能研究81301736,主持
2. 成都市科技局 结肠癌对5-Fu耐药性的机制及潜在药物靶点的研究2015-HM01-00071-SF 主持
发表文章:
Ziqi Zhang, Tong Sun, Yuxi Chen, Shu Gong, Xiye Sun, Fangdong Zou,Rui Peng*, CCL25/CCR9 Signal Promotes Migration and Invasion in Hepatocellular and Breast Cancer Cell Lines,DNA and Cell Biology, 2016, DOI: 10.1089/dna.2015.3104
Kuihua Huang, Jiabo Deng, JianqiuYu, Zhiguang Cai, Yuliang Liu,Rui Peng*, Complete mitochondrial genome sequence of the Asian golden cat,Catopuma temminckii.Mitochondrial DNA, 2016, 27(5):3118-3119
Shuai Tan, Jietian Xu, Fangdong Zou, Quekun Peng*,Rui Peng*, The complete mitochondrial genome of leopard cat,Prionailurus bengalensis chinensis(Carnivora:Felidae).Mitochondrial DNA,2016, 27(5):3073-3074
Rui Peng, Jingshan Tong, Hua Li, Bisong Yue, Fangdong Zou, Jian Yu, and Lin Zhang., 2013. Targeting Bax interaction sites revealed that only homo-oligomerization sites are essential for its activation.Cell Death and Differentiation20,744-754 (Faculty 1000).
Peng, R., Zhang, P., Xiong, J.L., Gu, H.J., Zeng, X.M., Zou, F.D., 2010. Rediscovery ofProtohynobius puxiongensis(Caudata: Hynobiidae) and its phylogenetic position based on complete mitochondrial genomes.Mol Phylogenet Evol56, 252-258
Peng Rui, Bo Zeng, Xiuxiang Meng, Bisong Yue, Zhihe Zhang, Fangdong Zou, The complete mitochondrial genome and phylogenetic analysis of the giant panda (Ailuropoda melanoleuca),Gene, 2007, 397: 76-83
Lichun Jiang, Gaochao Wang,Rui Peng, Quekun Peng, Fangdong Zou, 2014,Phylogenetic and molecular dating analysis of Taiwan Blue Pheasant (Lophura swinhoii),Gene, 539: 21–29
Lichun Jiang, Gaochao Wang, Shuai Tan, Shu Gong, Min Yang, Quekun Peng,Rui Peng, Fangdong Zou, 2013,The complete mitochondrial genome sequence analysis of Tibetan argali (Ovis ammon hodgsoni): Implications of Tibetan argali and Gansu argali as the same subspecies,Gene, 521: 24-31
Dudgeon, C.,Peng, R., Wang, P., Sebastiani, A., Yu, J., Zhang, L., 2012. Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3beta and NF-kappaB to suppress tumor cell growth.Oncogene.31, 4848-4858
Zheng, Y.C.,Peng, R., Kuro-O, M., Zeng, X.M., 2011. Exploring Patterns and Extent of Bias in Estimating Divergence Time from Mitochondrial DNA Sequence Data in a Particular Lineage: A Case Study of Salamanders (Order Caudata).Mol Biol Evol28, 2521-2535
Dudgeon, C., Wang, P., Sun, X.,Peng, R., Sun, Q., Yu, J., Zhang, L., 2010. PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01.Molecular cancer therapeutics9, 2893-2902
Xia, Y., Gu, H.F.,Peng, R., Chen, Q., Zheng, Y.C., Murphy, R.W., Zeng, X.M., 2012. COI is better than 16S rRNA for DNA barcoding Asiatic salamanders (Amphibia: Caudata: Hynobiidae).Mol Ecol Resour12, 48-56
Gu, H.F., Xia, Y.,Peng, R., Mo, B.H., Li, L., Zeng, X.M., 2011. Authentication of Chinese Crude Drug Gecko by DNA Barcoding.Nat Prod Commun6, 67-71
Liu Xu, Bo Zeng,Rui Peng, Fangdong Zou, Bisong Yue, Molecular cloning and sequence analysis of the gene encoding interleukin 6 of the giant panda (Ailuropoda melanoleuca),Journal of Natural History, 2008, 42: 2585-2591
Gaochao Wang, Quekun Peng, Liyuan Wu, Tao Wang,Rui Peng, Li Li, Xiaomao Zeng, Fangdong Zou, 2012 , Nuclear and mitochondrial DNA reveals significant intraspecific genetic differentiation of tokay gecko in southern China and northern Vietnam,Journal of Zoology, 287, 215-223